Participants

To achieve the challenging tasks of Targetfish, we brought together 30 partners from 10 EU member states, 2 associated countries and 1 International Cooperation Partner Country (Chile).map corrected 10-9

 

1.  Wageningen Universiteit, Netherlands

cbi.targetfish@wur.nl

Principal investigators:  Geert Wiegertjes, Maria Forlenza, Carmen Embregts

Research focus: characterization of the immune responses induced by adjuvants and the development of vaccines against CyHV3 and SVCV.

Geert Wiegertjes

Geert Wiegertjes

Maria Forlenza

Maria Forlenza

Carmen Embregts

Carmen Embregts

2. Aarhus University, Denmark

Principal investigators: Niels Lorenzen, Ellen Lorenzen, Jesper Skou Rasmussen, Dennis Bela-ong, Dagoberto Sepulveda

Research focus: screening of novel expression systems for antigens and mass delivery of DNA vaccines to fish, responsible for performing in vivo experiments with VHSV in rainbow trout and turbot.

Niels Lorenzen

Niels Lorenzen

Ellen Lorenzen

Ellen Lorenzen

3. The University Court of the University of Aberdeen, UK

Principal investigators: Chris Secombes, Sam Martin, Jun Zou, Tiehui Wang

Research focus: studying the potential role of fish cytokines as vaccine adjuvants, the use of bacteriophages for vaccine and adjuvant delivery and the effects on T cell polarisation and cellular immunity in protection.

Chris Secombes

Chris Secombes

4. The Scottish Ministers Acting Through Marine Scotland, UK

Principal investigators: Bertrand Collet, Catherine Collins

Research focus: optimising a vaccine for PDV in Atlantic salmon, exploring T cell modulating cytokines as adjuvants and establishing non lethal tests for the prediction of efficacy.

Bertrand Collet

Bertrand Collet

Catherine Collins

Catherine Collins

5. Friedrich Loeffler Institut – Bundesforschungsinstitut Fuer Tiergesundheit, Germany

Principal investigators: Uwe Fischer, Takuya Yamaguchi

Research focus: vaccine development in rainbow trout and carp, including the efficacy testing of DNA-vaccines and baculoviral vector vaccines for mass delivery. Provide and test DAMP based adjuvants and study cell-mediated immune responses.

uwe

Uwe Fischer

Takuya Yamaguchi

Takuya Yamaguchi

 

 

6. Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria, Spain

Principal investigators: Carolina Tafalla, Jaime Pignatelli Garrigós

Research focus: optimization/ prediction of efficacy of VHSV vaccines in rainbow trout and turbot, also studying immune mechanisms that may correlate with protection in these species.

Carolina Tafalla

Carolina Tafalla

Jaime Pignatelli Garrigós

Jaime Pignatelli Garrigós

 7. Universitat Autonoma de Barcelona, Spain

Principal investigators: Oriol Sunyer, David Parra

Research focus: dissecting the mucosal humoral and cellular immunity in the protection conferred by effective immersion and oral vaccines.

Oriol Sunyer

Oriol Sunyer

David Parra

David Parra

8. Universita Degli Studi Della Tuscia, Italy

Principal investigators: Giuseppe Scapigliati, Francesco Buonocore, Simona Picchietti

Research focus: experimental work related to sea bass by including novel vaccination strategies for VERV, use of adjuvants, and studies related to the immune responses in correlation with protection in this species.

Giuseppe Scapligiati

Giuseppe Scapligiati

Francesco Buonocore

Francesco Buonocore

Simona Picchietti

Simona Picchietti

9. Institut National De La Recherche Agronomique, France

Principal investigators: Pierre Boudinot, Christelle Langevin, Susana Magadán

Research focus: dissection of the immune response in successful vaccination strategies in salmonids, with a special focus on the mechanisms that condition long-term memory in fish.

Pierre Boudinot

Pierre Boudinot

Christelle Langevin

Christelle Langevin

Susana Magadán

Susana Magadán

 10. Norges Veterinaerhogskole, Norway

Principal investigators: Øystein Evensen, Hetron M. Mungang’andu

Research focus: IPNV and PD virus immunization studies, design of adjuvants for immersion delivery (IPNV) and vector design (PD virus).

Oystein Evensen

Oystein Evensen

 11. The University Of Stirling, UK

Principal investigators: Alexandra Adams, Kim Thompson, Rowena Hoare

Research focus: testing and monitoring vaccine efficacy, development and testing of a vaccine to prevent RTFS in rainbow trout and Atlantic salmon, including the testing of various adjuvants and novel mass delivery methods.

Alexandra Adams

Alexandra Adams

Kim Thompson

Kim Thompson

Rowena Hoare

Rowena Hoare

12. Istituto Zooprofilattico Sperimentale delle Venezie, Italy

Principal investigators: Calogero Terregino, Anna Toffan

Research focus: perform VERV/VNN vaccination /challenge trials under controlled conditions. Collecting identified tissues during the experiments and submitted to relevant partners for further investigations.

Anna Toffan

Anna Toffan

Francesco Pascoli

Francesco Pascoli

 

13. Københavns Universitet, Denmark

Principal investigators: Kurt Buchmann, Per W. Kania, Moonika H. Marana, Jiwan Kumar Chettri

Research focus: contribute to production of a subunit vaccine targeting furunculosis in mariculture of rainbow trout.

Kurt Buchmann

Kurt Buchmann

Per W. Kania

Per W. Kania

Moonika H. Marana

Moonika H. Marana

Jiwan Kumar Chettri

Jiwan Kumar Chettri

14. Výzkumný ústav veterinárního lékarství, Czech Republic

Principal investigators: Tomáš Veselý, Dagmar Pokorová

Research focus: VRI will be involved especially in the experimental infections to be performed in carp.

Tomás Veselý

Tomás Veselý

Dagmar Pokorová

Dagmar Pokorová

15. The Hebrew University of Jerusalem, Israel

Principal investigators: Lior David,  Roni Tadmor

Research focus: Cy-HV3 vaccination of carp families from various strains using several vaccines. The vaccinated fish will be challenged with the virulent virus to test the vaccination efficiency.

Lior David

Lior David

16. University Murcia, Spain

Principal investigators: Victoriano Mulero, Jorge Galindo-Villegas

Research focus: development of adjuvants in WP3 and their validation and testing for seabream.

Victoriano Mulero

Victoriano Mulero

Jorge Galindo-Villegas

Jorge Galindo-Villegas

17. Tethys Aquaculture Limited, UK

Principal investigators: Patrick Smith

Research focus: amplifies the research outputs in products and services that fit the aquaculture industry needs.

Patrick Smith

Patrick Smith

18. PatoGen Analyses AS, Norway

Principal investigators: Vidar Aspehaug, Magnus Devold

Research focus: development of Real-Time PCR-assays for detection and typing of pathogens, Q-PCR assays for differentiation between pathogen variants, & Q-PCR assays for differentiation between vaccinated and infected fish.

Vidar Aspehaug

Vidar Aspehaug

 

19. Fishlab, Denmark

Principal investigators: Kirsten Engell-Sørensen, Louise Hjorth Nørremark

Research focus: supply healthy, vaccinated and non-vaccinated turbot larvae, fry as well as eggs for experimental purposes, will optimize different vaccination protocols and will develop oral vaccination methodology by use of bioencapsulation using live feed (two species of calanoid copepods, Artemia and rotifers).

Kirsten Engell-Sorensen

Kirsten Engell-Sørensen

Louise Hjorth Norremark

Louise Hjorth Nørremark

20. Naxo OÜ, Estonia

Principal investigators: Juri Sober, Indrek Toots, Kaia Talts

Research focus: developing monoclonal antibodies against different fish viruses, as well as antibodies necessary to study protective immune responses in the different fish species addressed by TargetFish.

Juri Sober

Juri Sober

21. Ridgeway Biologicals, UK

Principal investigators: Tim Wallis, Terry Field

Research focus: carry out experiments characterising the secreted proteomes of Edwardsiella tarda. Responsible for the culture, expression and purification of antigens p and blending them with the appropriate adjuvants identified into prototype vaccines.

tim

Tim Wallis

Terry Field

Terry Field

22. Rossi A/S, Denmark

Principal investigators: Torben Rød

Research focus: develop vaccination machines of fry. New working procedures as well as injection machines for small-size fish will be optimised, provided and implemented.

 

23. Ingeniatrics Tecnologias S.L., Spain

Principal investigators: María Flores

Research focus: participate in the microencapsulation of different fish vaccines for oral or immersion vaccination in alginate derivatives.

Maria Flores

Maria Flores

24. BigDNA, UK

Principal investigators: John March

Research focus: developing a strategy for the delivery of antigens for different fish vaccines through the use of bacteriophages.

john MArch

John March

25. W42 Industrial Biotechnology GmbH, Germany

Principal investigators: Ansgar Stratmann, Ulrich Giesecke

Research focus: support the development of production strains for different virus-proteins through the development of different purification/enrichment strategies.

Ansgar Stratmann

Ansgar Stratmann

26. Aquark, Greece

Principal investigators: Panos Christofilogiannis, Joanna Tavla

Research focus: field testing and design of effective vaccination strategies and delivery protocols.

Panos Christofilligianis

Panos Christofilogiannis

Joanna Tavla

Joanna Tavla

27. CentroVet, Chile

Principal investigators: David Farcas, Jaime Tobar

Research focus: establishment of oral vaccination strategies for different fish pathogens using the

MicroMatrix™ Technology (ABN).

David Farcas

David Farcas

Jaime Tobar

Jaime Tobar

28. Danish Aquaculture Association, Denmark

Principal investigators: Niels Henrik Henriksen

Research focus: participate in the field trials foreseen in TargetFish.

Niels Henrik Henriksen

Niels Henrik Henriksen

 

29. BioMar A/S, Denmark

Principal investigators: Anne Hjørngaard Lauritsen, Ralph Bickerdike, Trygve Sigholt

Research focus: collaborate in the development of oral vaccination strategies and delivery methods for different fish vaccines.

Trygve Sigholt

Trygve Sigholt

30. Bionaturis, Spain

Principal investigators: Juan José Infante, Ana de la Heras, Rosa Osuna

Research focus: development and production of VHSV and nodavirus antigenic proteins by using its proprietary platform FLYLIFE to develop oral vaccines against these viruses.

Ana de las Heras

Ana de las Heras